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Original article

Vol. 155 No. 1 (2025)

Impact of atrial fibrillation on productivity in working-age patients: an analysis of Swiss-AF prospective cohort study data

Cite this as:
Swiss Med Wkly. 2025;155:3669
Published
02.01.2025

Summary

AIMS: We aimed to explore atrial fibrillation (AF)-induced productivity losses in working-age atrial fibrillation patients and to estimate atrial fibrillation-related indirect costs.

METHODS: Between 2014 and 2017, the Swiss Atrial Fibrillation prospective cohort study (Swiss-AF) enrolled 217 working-age patients with documented atrial fibrillation. Self-reported changes in professional activity and the reasons thereof were descriptively analysed over 8 years of follow-up or until patients reached the retirement age. Results were put into perspective, and indirect costs were planned to be estimated, through comparison with a general population-based, age-, sex- and year-matched comparison sample from the Swiss labour force survey (SLFS).

RESULTS: Of 217 analysed Swiss-AF patients, 14.7% reported a professional activity change (9.2% stop, 5.5% reduction) due to atrial fibrillation before the end of observation. Of those working at enrolment (n = 157), 3.8% had a subsequent professional activity change due to atrial fibrillation, 11.6% due to other reasons. Patients were more likely to report an impact of atrial fibrillation on professional activity if they had had atrial fibrillation longer and were closer to the retirement age. Slightly fewer Swiss-AF patients were employed (75%) than in the comparison sample (77%). For those working however, the degree of employment was higher (88% vs 83%). Lack of differences between the Swiss-AF patients and the comparison sample indicated no relevant indirect costs of atrial fibrillation due to lost productivity.

CONCLUSION: Only a minority of atrial fibrillation patients reported a negative impact of atrial fibrillation on their professional activity. Professional activity changes due to other reasons were reported more frequently. Compared with the general population, atrial fibrillation did not cause distinct differences.

References

  1. Morillo CA, Banerjee A, Perel P, Wood D, Jouven X. Atrial fibrillation: the current epidemic. J Geriatr Cardiol. 2017 Mar;14(3):195–203.
  2. Foster-Witassek F, Aebersold H, Aeschbacher S, Ammann P, Beer JH, Blozik E, et al.; Swiss‐AF Investigators. Longitudinal Changes in Health-Related Quality of Life in Patients With Atrial Fibrillation. J Am Heart Assoc. 2023 Nov;12(21):e031872. doi: https://doi.org/10.1161/JAHA.123.031872
  3. Rohrbacker NJ, Kleinman NL, White SA, March JL, Reynolds MR. The burden of atrial fibrillation and other cardiac arrhythmias in an employed population: associated costs, absences, and objective productivity loss. J Occup Environ Med. 2010 Apr;52(4):383–91. doi: https://doi.org/10.1097/JOM.0b013e3181d967bc
  4. Bernt Jørgensen SM, Gerds TA, Johnsen NF, Gislason G, El-Chouli M, Brøndum S, et al. Diagnostic group differences in return to work and subsequent detachment from employment following cardiovascular disease: a nationwide cohort study. Eur J Prev Cardiol. 2023 Jan;30(2):182–90. doi: https://doi.org/10.1093/eurjpc/zwac249
  5. Walker-Bone K, D’Angelo S, Linaker CH, Stevens MJ, Ntani G, Cooper C, et al. Morbidities among older workers and work exit: the HEAF cohort. Occup Med (Lond). 2022 Oct;72(7):470–7. doi: https://doi.org/10.1093/occmed/kqac068
  6. Leijten FR, van den Heuvel SG, Ybema JF, van der Beek AJ, Robroek SJ, Burdorf A. The influence of chronic health problems on work ability and productivity at work: a longitudinal study among older employees. Scand J Work Environ Health. 2014 Sep;40(5):473–82. doi: https://doi.org/10.5271/sjweh.3444
  7. Conen D, Rodondi N, Mueller A, Beer J, Auricchio A, Ammann P, et al. Design of the Swiss Atrial Fibrillation Cohort Study (Swiss-AF): structural brain damage and cognitive decline among patients with atrial fibrillation. Swiss Med Wkly. 2017 Jul;147(2728):w14467.
  8. Swiss Labour Force Survey | Fact sheet | Federal Statistical Office. Accessed October 17, 2023. Available from: https://www.bfs.admin.ch/bfs/en/home/statistics/work-income/surveys/slfs.assetdetail.20565829.html
  9. Swiss Labour Force Survey (SLFS) | Federal Statistical Office. Accessed October 17, 2023. Available from: https://www.bfs.admin.ch/bfs/en/home/statistics/work-income/surveys/slfs.html
  10. Ericson L, Bergfeldt L, Björholt I. Atrial fibrillation: the cost of illness in Sweden. Eur J Health Econ. 2011 Oct;12(5):479–87. doi: https://doi.org/10.1007/s10198-010-0261-3
  11. Johnsen SP, Dalby LW, Täckström T, Olsen J, Fraschke A. Cost of illness of atrial fibrillation: a nationwide study of societal impact. BMC Health Serv Res. 2017 Nov;17(1):714. doi: https://doi.org/10.1186/s12913-017-2652-y
  12. Statistics | Eurostat. Accessed October 26, 2023. Available from: https://ec.europa.eu/eurostat/databrowser/view/NAMA_10_FTE__custom_8126687/default/table?lang=en
  13. Jönsson L, Eliasson A, Kindblom J, Almgren O, Edvardsson N. Cost of illness and drivers of cost in atrial fibrillation in Sweden and Germany. Appl Health Econ Health Policy. 2010;8(5):317–25. doi: https://doi.org/10.2165/11319880-000000000-00000