Vitamin  K antagonists are hard to beat by the price – are they? Some answers, new  questions and the GPs’ dilemma

Jürg H. Beer

doi:10.4414/smw.2013.13739

Viewpoint

Vol. 143 No. 0102 (2013)

Vitamin K antagonists are hard to beat by the price – are they? Some answers, new questions and the GPs’ dilemma

Jürg H. Beer

Cite this as:: Swiss Med Wkly. 2013;143:w13739
Published: 30.12.2012

References

Mahler MP, Züger K, Kaspar K, Haefeli A, Jenni W, Leniger T, et al. A cost analysis of the first year after stroke – early triage and inpatient rehabilitation may reduce long term costs. Swiss Med Wkly. 2008;138(31-32):459–65.
Pletscher M, Plessow R, Eichler K, Wieser S. Cost-effectiveness of dabigatran for stroke prevention in atrial fibrillation in Switzerland. Swiss Med Wkly. 2013;143:w13732 http://www.smw.ch/content/smw-2013-13732/.
Kirley K, Qato DM, Kornfield R, Stafford RS, Alexander GC. National trends in oral anticoagulant use in the Unites States, 2007 to 2011. Circulation: Cardiovascular Quality and Outcomes. 2012; 5. 12‒10394.
Sha SV, Gage BF. Cost-effectiveness of dabigatran for stroke prophylaxis in artrial fibrillation / clinical perspective. Circulation. 2011;123(22):2562–70.
Freeman JV, Zhu RP, Owens DK, Garber AM, Hutton DW, Go AS, et al. Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation. Ann Int Med. 2011;154:1.
Legrand M, Mateo J, Aribaud A, Ginisty S, Eftekhari P, Tran Ba Huy P, et al. The use of dabigatran in elderly patients. Arch Int Med. 2011;171:1285.
Wieloch M, Själander A, Frykman V, Rosenqvist M, Eriksson N, Svensson PJ. Anticoagulation control in Sweden: reports of time in therapeutic range, major bleeding, and thrombo-embolic complications from the national quality registry AuriculA. Eur Heart J. 2011;32:2282–9.
Wallentin L, Yusuf S, Ezekowitz MD, Alings M, Flather M, Franzosi MG, et al. Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial. Lancet. 2010;376:975–83.
Naderi SH, Bestwick JP, Wald DS. Adherence to drugs that prevent cardiovascular disease: m-analysis on 376,162 Patients. Am J Med. 2012;125:882–7.
Camm AJ, Lip G Y.H., De Caterina R, Savelieva I, Atar D, Hohnloser SH, et al. 2012 focused update of the ESC Guidelines for the management of atrial fibrillation. An update of the 2010 ESC Guidelines for the management of atrial fibrillation – developed with the special contribution of the European Heart Rhythm Association. Eur Heart J. 2012;33:2719–47.
Krejczy M, Harenberg J, Marx S, Obermann K, Wehling M. Comparison of cost-effectiveness of anticoagulation with dabigatran, rivaroxaban and apixaban in patients with non-valvular atrial fibrillation across countries. Blood (ASH Annual Meeting Abstracts). 2012;120:Abstract 1164.

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Vitamin K antagonists are hard to beat by the price – are they? Some answers, new questions and the GPs’ dilemma. Swiss Med Wkly [Internet]. 2012 Dec. 30 [cited 2025 Dec. 14];143(0102):w13739. Available from: https://www.smw.ch/index.php/smw/article/view/1804

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DOI:: https://doi.org/10.4414/smw.2013.13739

[1] Mahler MP, Züger K, Kaspar K, Haefeli A, Jenni W, Leniger T, et al. A cost analysis of the first year after stroke – early triage and inpatient rehabilitation may reduce long term costs. Swiss Med Wkly. 2008;138(31-32):459–65.

[2] Pletscher M, Plessow R, Eichler K, Wieser S. Cost-effectiveness of dabigatran for stroke prevention in atrial fibrillation in Switzerland. Swiss Med Wkly. 2013;143:w13732 http://www.smw.ch/content/smw-2013-13732/.

[3] Kirley K, Qato DM, Kornfield R, Stafford RS, Alexander GC. National trends in oral anticoagulant use in the Unites States, 2007 to 2011. Circulation: Cardiovascular Quality and Outcomes. 2012; 5. 12‒10394.

[4] Sha SV, Gage BF. Cost-effectiveness of dabigatran for stroke prophylaxis in artrial fibrillation / clinical perspective. Circulation. 2011;123(22):2562–70.

[5] Freeman JV, Zhu RP, Owens DK, Garber AM, Hutton DW, Go AS, et al. Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation. Ann Int Med. 2011;154:1.

[6] Legrand M, Mateo J, Aribaud A, Ginisty S, Eftekhari P, Tran Ba Huy P, et al. The use of dabigatran in elderly patients. Arch Int Med. 2011;171:1285.

[7] Wieloch M, Själander A, Frykman V, Rosenqvist M, Eriksson N, Svensson PJ. Anticoagulation control in Sweden: reports of time in therapeutic range, major bleeding, and thrombo-embolic complications from the national quality registry AuriculA. Eur Heart J. 2011;32:2282–9.

[8] Wallentin L, Yusuf S, Ezekowitz MD, Alings M, Flather M, Franzosi MG, et al. Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial. Lancet. 2010;376:975–83.

[9] Naderi SH, Bestwick JP, Wald DS. Adherence to drugs that prevent cardiovascular disease: m-analysis on 376,162 Patients. Am J Med. 2012;125:882–7.

[10] Camm AJ, Lip G Y.H., De Caterina R, Savelieva I, Atar D, Hohnloser SH, et al. 2012 focused update of the ESC Guidelines for the management of atrial fibrillation. An update of the 2010 ESC Guidelines for the management of atrial fibrillation – developed with the special contribution of the European Heart Rhythm Association. Eur Heart J. 2012;33:2719–47.

[11] Krejczy M, Harenberg J, Marx S, Obermann K, Wehling M. Comparison of cost-effectiveness of anticoagulation with dabigatran, rivaroxaban and apixaban in patients with non-valvular atrial fibrillation across countries. Blood (ASH Annual Meeting Abstracts). 2012;120:Abstract 1164.