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Detection of HLA antibodies prior to renal transplantation:
prospects and limitations of new assays

 
Amico P, Hönger G, Mayr M, Schaub S.
Swiss Med Wkly 2008;138(33–34):472–476

Review article
Peer reviewed article

 
Summary
 
Donor-specific HLA antibodies are responsible for most early renal allograft rejections and allograft losses. Therefore, detection of HLA antibodies prior to transplantation is an important step in the evaluation of renal allograft recipients. In this mini-review we will describe recent advances in the techniques used to detect donorspecific HLA antibodies with emphasis on their potential application for patient management and their current limitations.

Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland



Copyright © 2008 EMH Swiss Medical Publishers Ltd.