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Haematopoietic stem cell transplantation in Switzerland.
 
Passweg J, Baldomero H, Chapuis B, Leibundgut K, Schanz U, Gratwohl A, for the STABMT Board.
Swiss Med Wkly 2006;136:50-58

Original article
Peer reviewed article

 
Summary

Report from the Swiss Transplant Working Group for Blood and Marrow Transplantation (STABMT) Registry 1997–2003
In 1997, the Swiss Transplant Working Group Blood and Marrow Transplantation (STABMT) initiated a mandatory national registry for all haematopoietic stem cell transplants (HSCT) in Switzerland. As of 2003, information was collected of 2010 patients with a first HSCT (577 allogeneic (29%) and 1433 autologous (71%) HSCT) and 616 additional re-transplants. This included 1167 male and 843 female patients with a median age of 42.4 years (range 0.2–76.6 years). Main indications were leukaemias (592; 29%) lymphoproliferative disorders (1,061; 53%), solid tumours (295; 15%) and non-malignant disorders (62; 3%). At the time of analysis 1,263 patients were alive (63%), 747 had died (37%). Probability of survival, transplant related mortality or relapse at 5 years was 52%, 21%, 36% for allogeneic and 54%, 5%, 60% for autologous HSCT. Outcome depended on indication, donor type, stem cell source and age of patient. HSCT is an established therapy in Switzerland. These data describe current practice and outcome.

Division of Haematology, University Hospital, Basel, Switzerland
Division of Haematology, University Hospital, Geneva, Switzerland
Division of Haematology/Oncology, Department of Paediatrics, University Hospital, Berne, Switzerland
Division of Haematology, University Hospital, Zurich, Switzerland



Copyright © 2006 EMH Swiss Medical Publishers Ltd.